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Oncogene Activation via Chromosomal Translocation

The translocatiion that creates the Philadelphia chromosome.

Translocation of proto-octogenes

Chromosomal translocation in Burkitt's lymphoma leads to the activation of myc oncogene.

(Damjanov, Ivan. Pathobiology for the Health-Related Professions, 1996, p. 95)

Chromosomal translocations which activate oncogenes

(Strachan, Tom and Andrew P. Read. Human Molecular Genetics, 1996, p. 465)
 

© 2005 Center for Environmental Health