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Protein p53 and Tumor Suppressor Genes

Mutations in the p53 protein.

(Harris, Curtis C. p53: "At the Crossroads of Molecular Carcinogenesis and Risk Assessment." Science, Vol. 262, December 24, 1993, p. 1980-1981.)

For more information on p53, also see: "Molecule of the Year: p53 Sweeps Through Cancer Research". Science, Vol. 262, December 24, 1993, p. 1958-1959.